17 U.S. Code § 107 - Limitations on exclusive rights: Fair use
Notwithstanding the provisions of sections 106 and 106A, the fair use of a copyrighted work, including such use by reproduction in copies or phonorecords or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use the factors to be considered shall include—
(1) the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes [all mirrored content falls under this clause, any ads present are mirrored from the original site, mirrored content earns me no revenue whatsoever];
(2) the nature of the copyrighted work [this is a unique resource for the mentally ill, and preservation of it can be argued to be incredibly important];
(3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and
(4) the effect of the use upon the potential market for or value of the copyrighted work. [absolutely none whatsoever, as the original work no longer exists anywhere else (outside of whatever bits and pieces archive.org managed to capture) - the original site was intermittantly completely unavailable for a extended period of time before its SSL certificate expired (and was never renewed), and eventually the site went offline for good, then finally the DNS records were removed at some point prior to May 2018, so at this point it is well beyond the 'dead and rotting' stage]
The fact that a work is unpublished shall not itself bar a finding of fair use if such finding is made upon consideration of all the above factors.

This domain is not controlled by Jerod Poore, and I will NOT continue redirecting traffic from this domain to crazymeds.us [as I formerly did] while Jerod continues with his immature temper tantrum over adblock or continues to fail to maintain his site, fucking over his entire community and countless visitors in the process. [belated clarification: with specific regards to the adblock drama I was referring to Poore at one point replacing his entire site with a single page complaining about the amount of revenue lost to users with ad blocking active, which is something that I took extreme exception to because this affected ALL visitors to the site regardless of if or if not they were actually using ad blocking]
This mirror is unfortunately incomplete (and very slightly outdated), as /CrazyTalk/ was not included when I scraped the site (it was far too large to scrape given the site's extremely poor performance, my wish to avoid worsening the poor performance further, and other factors). If you're looking for a replacement forum, I suggest visiting https://www.crazyboards.org/forums/. There are issues with many of the mirrored pages, I am working on identifying and fixing them, but I do not have the time to address every single issue at this moment (although by now the majority of these issues have been resolved). Dynamic content is obviously completely broken (this is beyond my control), and the loss of /CrazyTalk/ is quite bad given how much good user-generated info was on there, but you have Jerod to "thank" for that. Maybe I'll bring it back online at some point, but it wouldn't be the same as before. For now, I suggest visiting CrazyBoards instead.
Note (Oct 9 2018): Infrequent additional updates regarding the status of this site will be posted on https://info.crazymeds.net

1.  Crazy Meds with FDA Approval to Treat Migraines, Other Headaches, Fibromyalgia and various types of Neuropathic Pain

Most drugs used to treat pain1 are either antiepileptic drugs (AEDs), or antidepressants that have a positive effect on the neurotransmitter norepinephrine, usually SNRIs like Cymbalta or TCAs like amitriptyline. AEDs are also used to prevent migraines.

Brand/Trade namegeneric nameApprovals
carbamazepinecarbamazepineTrigeminal Neuralgia, Glossopharyngeal Neuralgia
Cymbaltaduloxetine hydrochlorideFibromyalgia, Diabetic Peripheral Neuropathic Pain, Chronic Musculoskeletal Pain
Depakotedivalproex sodiumMigraine prophylaxis
divalproex sodiumdivalproex sodiumMigraine prophylaxis
duloxetineduloxetine hydrochlorideFibromyalgia, Diabetic Peripheral Neuropathic Pain, Chronic Musculoskeletal Pain
gabapentingabapentinPostherpetic Neuralgia
InderalpropranololMigraine prophylaxis
LyricapregabalinPostherpetic Neuralgia, Diabetic Peripheral Neuropathy, Fibromyalgia
milnacipranmilnacipran hydrochlorideFibromyalgia
NeurontingabapentinPostherpetic Neuralgia
pregabalinpregabalinPostherpetic Neuralgia, Diabetic Peripheral Neuropathy, Fibromyalgia
Stavzorvalproic acid delayed releaseMigraine prophylaxis
TegretolcarbamazepineTrigeminal Neuralgia, Glossopharyngeal Neuralgia
TopamaxtopiramateMigraine prophylaxis
topiramatetopiramateMigraine prophylaxis
valproic acid delayed releasevalproic acid delayed releaseMigraine prophylaxis


2.  Other Meds with FDA Approval to Treat Migraines, Other Headaches, and Neuropathic Pain

2.1  Serotonin Receptor Agonists (Triptans)

  • Zomig (zolmitriptan)
  • Amerge (naratriptan)
  • Frova (frovatriptan)
  • Axert (almotriptan)
  • Relpax (eletriptan)
  • Imitrex (sumatriptan)
  • Maxalt (rizatriptan)

There are conflicting data regarding the safety of mixing triptans with SSRIs or SNRIs.

  • I had a blanket warning about combining the two classes all over this site 2004 - 2009 due to the danger of serotonin syndrome.
  • The FDA caught up with me in 2006 when they issued this alert.
  • Since then it’s been standard practice to make sure no one takes one from column A and one from column B.
    • Except lots of people are probably still taking both.
  • Like I did, the FDA based its warning on a bunch of case reports.
    • As I have a crappy little website, my warning consisted of “talk to your doctor(s) about mixing these two meds that will result in an interaction with a greater than 0 chance of killing you.”
      • Or something like that.
    • When the FDA says essentially the same thing, doctors are the ones who stop prescribing one if you’re already taking the other.
    • Since then I’ve learned that the chance of serotonin syndrome is extremely low no matter what, and the likelihood of it killing you is lower yet.
    • Not only that, we have the best example of contradictory data and dueling studies ever!
  • Like I have, the FDA seems to have changed its mind regarding just how dangerous it is to mix triptans and SSRIs or SNRIs.
    • Have they rescinded their warning? Of course not! The FDA is never wrong. Even though it was updated in August 2013, look at it. Notice anything missing? Where’s Pristiq?
    • The real question is: where the hell is Viibryd? If any med on the planet is going to cause serotonin syndrome when mixed with a triptan it would by Viibryd.

As always talk to your doctor(s). If you have more than one doctor prescribing the medications that could be interacting with each other, try to get them to talk with each other. Good luck with that.

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Don’t worry about actually buying one. Windows shop and share the designs you’d like to buy. Do you have something better to do right now?

2.2  NSAIDs

  • Bayer Extra Strength Asprin
  • Cambia (diclofenac potassium)

2.3  Other

  • Botox (onabotulinumtoxinA)
  • Migranal (dihydroergotamine)

Stick to your AED-based treatment plan. Buttons and magnets, 2.25″ $4 & 3.5″ $4.50 the each
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3.  Crazy Meds Commonly Used Off-Label to Treat Migraines, Other Headaches, and Neuropathic Pain

Brand/Trade namegeneric nameApproved IndicationsOff-Label Uses


4.  Meds not Available in the US Approved to Treat Migraines & Neuropathic Pain

  • flunarizine - a calcium-channel blocker (like verapamil) and antihistamine approved to treat migraines

5.  Devices and other Non-Medication Treatments Proven to be Effective in Treating Migraines & Neuropathic Pain

These will stick around longer than AED side effects. More ways to be stuck-up at Straitjacket T-shirts. All stickers only $5
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6.  References

  1. Evans, Randolph W. “The FDA Alert on Serotonin Syndrome With Combined Use of SSRIs or SNRIs and Triptans: An Analysis of the 29 Case Reports.” MedGenMed. 2007; 9(3): 48. Published online Sep 5, 2007.
  2. Kogut, Stephen J. “Do Triptan Antimigraine Medications Interact with SSRI/SNRI Antidepressants? What Does Your Decision Support System Say?” Journal of Managed Care & Specialty Pharmacy. 2011 Sep;17(7):547-51.
  3. Virani, Adil S., K. Bezchlibnyk-Butler, and J. Jeffries Clinical Handbook of Psychotropic Drugs 18th edition Hogrefe & Huber Publishers 2009. ISBN:978–0889373693
  4. Silberstein, Stephen D., Michael J. Marmura Essential Neuropharmacology: The Prescriber’s Guide Cambridge University Press 2010. ISBN:978–0521136723

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1 Other than opioids, of course, or medications that treat the source of non-neuropathic pain, like steroids or other anti-inflammatory drugs.

2 Drug study I want to see: Botox vs. Acupuncture vs. placebo instead of Botox vs. sham Acupuncture vs. Acupuncture using Botox. The PI sheet for Botox really stresses the importance of where the injections are placed. I swear it looks like an acupuncture diagram. How much of Botox treatment's success is due to the paralytic effect of the toxin and how much, if any, is due to it being a form of acupuncture? Of course the injection sites need to be accurate as hell in order to not fuck up something, so the last part of the study may not be ethical.

3 Which is the main reason we don't discuss medical MJ on the forum. It turns into a holy war time sink. A close second is that smoking, or however you like to ingest your pot is one of the worst things anyone with bipolar disorder or schizophrenia can do. I'm positive all the pot I smoked is one of, if not the main reason I'm now treatment-resistant. I'm all for the full relegalization of cannabis and people who aren't as crazy as I am getting as high as they want to as often as they want to. I just want a warning label on it regarding bipolar and schizophrenia - even if 1% of pot-smoking nutjobs, at best, would pay attention to it - and more of the tax revenue that goes for mental health treatment programs to go to something other than drug rehab programs.

Last modified on Friday, 08 May, 2015 at 11:29:11 by JerodPoorePage Author Date created 15 May 2011
“Treatment Options for Migraines, Other Headaches, Fibromyalgia, and Neuropathic Pain” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/05/15
Citation options to copy & paste into your article:
Plain text:Poore, Jerod. “Treatment Options for Migraines, Other Headaches, Fibromyalgia, and Neuropathic Pain.” Crazymeds (crazymeds.net). (2011).
with Microdata: <span itemprop='citation'>Poore, Jerod. "Treatment Options for Migraines, Other Headaches, Fibromyalgia, and Neuropathic Pain." <em>Crazymeds (crazymeds.net)</em>.(2011).</span>
Linked:<a href="http://scholar.google.com/citations?user=5rkux7sAAAAJ&hl=en&oi=sra">Poore, Jerod</a>. <a href='https://crazymeds.net/pmwiki/pmwiki.php/MedClass/NP'>"Treatment Options for Migraines, Other Headaches, Fibromyalgia, and Neuropathic Pain"</a>. <a href="https://crazymeds.net/pmwiki/pmwiki.php/Main/HomePage"> <em>Crazymeds (crazymeds.net)</em></a>. (2011).
with Microdata:<span itemprop='citation'> <a href="http://scholar.google.com/citations?user=5rkux7sAAAAJ&hl=en&oi=sra">Poore, Jerod</a>. <a href='https://crazymeds.net/pmwiki/pmwiki.php/MedClass/NP'>"Treatment Options for Migraines, Other Headaches, Fibromyalgia, and Neuropathic Pain"</a>. <a href="https://crazymeds.net/pmwiki/pmwiki.php/Main/HomePage"> <em>Crazymeds (crazymeds.net)</em></a>. (2011).</span>

Page design and explanatory material by Jerod Poore, copyright © 2003 - 2015. All rights reserved.
Keep up with Crazymeds and and/or my slow descent into irreparable madness boring life. Pick your preferred social media target(s):

Almost all of the material on this site is by Jerod Poore and is copyright © 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, and 2015 Jerod Poore. Except, of course, the PI sheets - those are the property of the drug companies who developed the drugs the sheets are about - and any documents that are written by other people which may be posted to this site will remain the property of the original authors. You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder. That’s usually me, so just ask first. That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that’s OK to just do. Go for it! Please. As long as you include this copyright notice and something along the lines of following disclaimer, I’m usually cool with it.

All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. If you still have questions about a medication or condition that were not answered on any of the pages you read, please ask them on Crazy Talk: the Crazymeds Forum.
The information on Crazymeds pertains to and is intended for adults. While some information about children and adolescents is occasionally presented (e.g. US FDA approvals), pediatric-specific data such as dosages, side effects, off-label applications, etc. are rarely included in the articles on drugs or discussed on the forum. If you are looking for information regarding meds for children you’ll have to go somewhere else. Plus we are big pottymouths and talk about S-E-X a lot.
Know your sources!
Nobody on this site is a doctor, a therapist, or a pharmacist. We don’t portray them either here or on TV. Only doctors can diagnose and treat an illness. While it’s not as bad as it used to be, some doctors still get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don’t be a cyberchondriac, thinking you have every disease you see a website about, or that you’ll get every side effect from every medication1. Self-prescribing is as dangerous as buying meds from fraudulent online pharmacies that promise you medications without prescriptions.
All information on this site has been obtained from the medications’ product information / summary of product characteristic (PI/SPC) sheets and/or medication guides - which is all you get from sites like WebMD, RxList, NAMBLA NAMI, etc., the sources that are referenced throughout the site, our personal experience and the experiences family, friends, and what people have reported on various reputable sites all over teh intergoogles. As such the information presented here is not intended as a substitute for real medical advice from your real doctor, just a compliment to it. You should never, ever, replace what a real doctor tells you with something from a website on the Internet. The farthest you should ever take it is getting a second opinion from another real doctor. Educate yourself - always read the PI/SPC sheet or medication guide/patient information leaflet (PIL) that comes with your medications and never ever throw them away. OK, you can throw away duplicate copies, but keep at least one, as that’s your proof of purchase of having taken a med in case a doctor doubts your medical history. Plus they take up less space than a bottle, although keeping one inside of a pill bottle is even better.
Crazymeds is not responsible for the content of sites we provide links to. We like them, or they’re paid advertisements, or they’re something else we think you should read to help you make an informed decision about a particular med. Sometimes they’re more than one of those things. But what’s on those sites is their business, not ours.
Very little information about visitors to this site is collected or saved. From time to time I look at search terms used and which pages they bring up in an effort to make the information I present more relevant. And the country of origin, just because I’m geeky like that. That’s about it. Depending on how you feel about Schrodinger, our privacy policy should either assuage or exacerbate your paranoia.
Crazymeds is optimized for ridiculously large screens and browsers that don’t block ads. I use Firefox and Chrome, running under Windows 72. On a computer that sits on top of my desk. With a 23 inch monitor. Hey, at least you can make the text larger or smaller by clicking on the + or - buttons in the upper right hand corner. If you have Java enabled. Like 99% of the websites on the planet, Crazymeds is hosted on domain running an open source operating system with a variety of open source applications, including the software used to display what you’ve been reading. As such Crazymeds is not responsible for whatever weird shit your browser does or does not do when you read this site3.
No neurologists, psychiatrists, therapists or pharmacists were harmed in the production of this website. Use only as directed. Void where prohibited. Contains nuts. Certain restrictions may apply. All data are subject to availability. Not available on all mobile devices, in the 12 Galaxies Guiltied to a Zegnatronic Rocket Society, or in all dimensions of reality. Hail Xenu!

‘Everything is true, nothing is permitted.’ - Jerod Poore

1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.

2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more. With TOS Star Trek movies you don’t want to bother watching the odd-numbered ones. With Microsloth OS you don’t want to buy and install the even-numbered ones. Anyone who remembers ME and Vista knows what I mean.

3 Have I mentioned how open source operating systems for commercial applications is one of the dumbest ideas in the history of dumb ideas?* I don’t even need my big-ass rant any more. Heartbleed has made my case for me. And that’s just the one that got all the media attention. The very nature of an open source operating system makes security as much of an illusion as anonymity on teh Intergoogles. Before you flip out too much: the domain Crazymeds is hosted on uses a version of SSL that is not affected by the Heartbleed bug. That’s one of the many reasons why I pay a lot of money and keep this site on Lunarpages.

* Yes, I know I’m using open source browsers. I also test the site using the now-defunct IE and Safari browsers. Their popularity - and superiority - killed IE and Safari, so that’s why I rely on the open source browsers. It’s like brand vs. generic meds. Sometimes the generic is better than the brand.

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