17 U.S. Code § 107 - Limitations on exclusive rights: Fair use
Notwithstanding the provisions of sections 106 and 106A, the fair use of a copyrighted work, including such use by reproduction in copies or phonorecords or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use the factors to be considered shall include—
(1) the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes [all mirrored content falls under this clause, any ads present are mirrored from the original site, mirrored content earns me no revenue whatsoever];
(2) the nature of the copyrighted work [this is a unique resource for the mentally ill, and preservation of it can be argued to be incredibly important];
(3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and
(4) the effect of the use upon the potential market for or value of the copyrighted work. [absolutely none whatsoever, as the original work no longer exists anywhere else (outside of whatever bits and pieces archive.org managed to capture) - the original site was intermittantly completely unavailable for a extended period of time before its SSL certificate expired (and was never renewed), and eventually the site went offline for good, then finally the DNS records were removed at some point prior to May 2018, so at this point it is well beyond the 'dead and rotting' stage]
The fact that a work is unpublished shall not itself bar a finding of fair use if such finding is made upon consideration of all the above factors.

This domain is not controlled by Jerod Poore, and I will NOT continue redirecting traffic from this domain to crazymeds.us [as I formerly did] while Jerod continues with his immature temper tantrum over adblock or continues to fail to maintain his site, fucking over his entire community and countless visitors in the process. [belated clarification: with specific regards to the adblock drama I was referring to Poore at one point replacing his entire site with a single page complaining about the amount of revenue lost to users with ad blocking active, which is something that I took extreme exception to because this affected ALL visitors to the site regardless of if or if not they were actually using ad blocking]
This mirror is unfortunately incomplete (and very slightly outdated), as /CrazyTalk/ was not included when I scraped the site (it was far too large to scrape given the site's extremely poor performance, my wish to avoid worsening the poor performance further, and other factors). If you're looking for a replacement forum, I suggest visiting https://www.crazyboards.org/forums/. There are issues with many of the mirrored pages, I am working on identifying and fixing them, but I do not have the time to address every single issue at this moment (although by now the majority of these issues have been resolved). Dynamic content is obviously completely broken (this is beyond my control), and the loss of /CrazyTalk/ is quite bad given how much good user-generated info was on there, but you have Jerod to "thank" for that. Maybe I'll bring it back online at some point, but it wouldn't be the same as before. For now, I suggest visiting CrazyBoards instead.
Note (Oct 9 2018): Infrequent additional updates regarding the status of this site will be posted on https://info.crazymeds.net


Part 1: Indications, efficacy, dosage, titration, discontinuation, pros and cons, adverse events, availability and how supplied.

> Abilify (aripiprazole) Review


The Abilify (aripiprazole) Overview is a briefer, more consumer-friendly version of this article. The information in this article comes from twelve separate pages, with more explanatory material, to which the overview links. The title of each section on both pages of this article is also a link to each of those pages.

Click here for Part 2: Warnings, clinical pharmacology, interactions, additional comments and consumer experiences

Abstract

Consumers need more information than what is provided in the patient information literature, but are intimidated by, or have no desire to read all of, the prescribing information for a drug. This review of the drug Abilify (aripiprazole) provides what the educated consumer wants, highlighting its use as, and comparing it with other {{$$drugclass2}}. Also discussed are off-label uses, efficacy, adverse events and how to mitigate them, titration and discontinuation schedules, clinical pharmacology, other aspects of using Abilify (aripiprazole), and consumer experiences.

Classification

Primary Drug Class

Abilify (aripiprazole) is in the Antipsychotics class of medications.

Additional Drug Categories

MoodStabilizers, Antidepressants

Indications

A review of Abilify’s prescribing information, the literature, and consumer experience. Regarding off-label applications: if something is to be considered as “clinically significant” there need to be large, double-blind studies or clinical trials in addition to lots of consumer experiences, otherwise it will still be considered as experimental.

FDA-Approved Indications

Schizophrenia

  • Acute (4–6 weeks) schizophrenia in adults and adolescents (13–17)
    • Both the PI sheet and the FDA’s page on Abilify’s approved indications are fuzzy on Abilify being approved for maintenance (long-term, i.e. six months or longer) use.
    • It’s extra-fuzzy with adolescents, as there was only one long-term clinical trial in the US, the results were a bit sketchy, and everyone thinks it’ll work as a maintenance med for kids based upon extrapolating the data from the adult trial.

Bipolar I Disorder

  • Acute (adults and children 10 and up) and maintenance (adults only) treatment of manic and mixed episodes.
  • Both as monotherapy (used by itself) and as an adjunct (add-on, used with) to lithium or Depakote (or other valproate).

Other Approved Indications

  • Adjunctive treatment of Major Depressive Disorder (MDD) in adults.
  • Irritability associated with Autistic Spectrum Disorder (ASD) in pediatric patients (aged 6 to 17 years) with irritability associated with autistic disorder.
    • As it’s known around here: parental embarrassment syndrome, because they often medicate the kids to deal with the parents’ irritability1.
  • Psychomotor agitation associated with Schizophrenia or Bipolar Mania
    • Only the intramuscular (IM) injection is approved for this.
    • “Psychomotor agitation” is defined in DSM-IV as “excessive motor activity associated with a feeling of inner tension”.
    • Which I find hilarious as this is essentially using Abilify to treat a condition that presents as (has the symptoms of) common side effects of Abilify.

Drugs sometimes have different approvals in different countries.2 Consumers want to know this if they are running out of treatment options; or if they are researching their treatment options they may wish to know if, and why, a medication is approved for something in the US but not anywhere else.

Approved Uses Outside of the US

In most places Abilify is approved only to treat bipolar disorder and schizophrenia.

Clinically Significant or Otherwise Common Off-Label Uses

Subsets/Variants of Approved Uses

Anxiety Spectrum Disorders

Miscellaneous Significant/Common Off-Label Uses

Less Common/Experimental Off-Label Uses

Failed off-label uses

Potentially dangerous off-label uses

  • Methamphetamine abuse. Not only did it increase the desire for meth, it made the meth suck less. If that’s not a dangerous off-label use I don’t know what is.
    • As soon as Abilify goes generic watch aripiprazole get mixed in with whatever passes for ‘high-quality’ meth to produce something like crack with a high that lasts for a day.
  • Alzheimer’s, dementia, age-related ‘agitation’ (i.e. Grandpa’s acting up again). Do not, under any circumstances, give Abilify or any other antipsychotic to someone who is old just because you can’t deal with their behavior. (See the Black Box Warning).
    • I was a Certified Nurses’ Aide. I worked in a nursing home. I had to deal with senile old people on a daily basis. My coworkers and I could have treated them a hell of a lot better than we did, but at least we didn’t give them Thorazine when they were being pains in the ass.
      • Unfortunately that wasn’t true for the even more understaffed swing- and graveyard-shifts.
    • You don’t need APs to deal with someone who is not schizophrenic or bipolar. You need to do something like this:
      • Put them in the TV room
      • Strap them to their wheelchair and lock the wheels
      • Put on something old people like to watch
      • Arrange them so you have the people who like to talk to each other close to each other, and those who can’t stand each other are the furthest apart
        • That last part was so not my job.
    • Yes, physically restraining them sucks, but it’s better than putting them on an AP.
    • Believe me, if it’s at the point where they were given an AP, they were probably restrained already. They just didn’t have any Matlock to watch or someone to complain with about kids and those baggy jeans they wear down at their knees.
    • There are better solutions for individuals. In a perfect world there would be the time and smart employees to find what they are.


Efficacy & Comparisons with Other

A review of prescribing information, the literature and consumer experiences. In addition to review sites, which don’t skew as negative as one would think, consumer experiences with medications are frequently reported on social media sites that have nothing to do with medications or illnesses. There is such a consistent overlap in many demographics (e.g. women with bipolar 2 and/or migraines and scrapbooking) to provide a great deal of data on efficacy and adverse reactions from a very natural environment where consumers discuss their conditions and how to treat them that is free of almost all prejudices regarding medications and other treatment options.

Onset of Action

Faster than Seroquel, but slower than most other AAPs. I.e. 3–7 days, with 3 days more likely when adding Abilify to an AD and 7 days more likely when using Abilify by itself.

Efficacy for its Approved Indications

Given its activating nature, Abilify is probably more likely to work as an add-on to treat depression or bipolar disorder than as monotherapy for bipolar disorder. I don’t yet have enough data for schizophrenia, other than 5mg a day takes 3-5 weeks to start working, and only enough better than placebo to get approved by the FDA.

OK, I have a little more data than that, but it’s still mostly from books and studies. I like having more anecdotal evidence.

For Off-Label Applications

Abilify versus Other Antipsychotics for Approved Indications

Bipolar Disorder

  • Abilify vs. Haldol (haloperidol) vs. Placebo for bipolar mania. This is one of the European clinical trials, so it was paid for by Bristol-Myers Squibb (BMS) and Otsuka Pharmaceuticals, the manufacturers of Abilify. Haldol? OK, they were looking only at mania, so Haldol qualifies as an active placebo. The results: A tie! Wait, what? Yup, Haldol was marginally more effective, but Abilify sucked somewhat less.

Schizophrenia

  • Abilify vs. Risperdal vs. Placebo for schizophrenia & schizoaffective disorders. This is another BMS & Otsuka-sponsored study, so you know Abilify is going to win. The results: A tie! Even with one hand tied behind its back, Risperdal was just as good as Abilify. Abilify was better for negative symptoms and Risperdal was better for positive symptoms. Abilify sucked a lot less for the big-ticket side effects of weight gain, hyperprolactinemia-associated adverse reactions (porno boobs, leaky tits, sexual dysfunction, etc.), and QT interval, but Risperdal is easier to keep down. Oddly enough movement disorders were identical, but this was high-dosage Abilify (20–30mg) vs. low target dosage (for schizophrenia) (6mg) Risperdal.
  • Abiliby vs. Risperdal or Seroquel or Zyprexa: which makes you less crazy while still letting you fuck like a crazed otter? This is an expanded look at the data from one of the European clinical trials, so it’s BMS & Otsuka-sponsored study, and you have to expect Abilify going to win. They just lumped the competition into one group, so there’s no way to tell how each of the other meds worked. The results: Abilify worked better and sucked a lot less, especially when it came to sex. Why am I not surprised?
  • Abilify vs. Zyprexa which one works better and sucks less when treating schizophrenia. This is an Eli Lily-sponsored clinical trial that taught me the official research name of which sucks less: “all cause discontinuation.” The results: In spite of the weight gain Zyprexa wins. Anyone surprised? That Zyprexa works better and faster is to be expected, even in a trial run by a neutral party, but when Abilify has an affect on weight, glucose, and triglycerides that make it look like a diabetes treatment, you’ve got to wonder about why so many people dropped it.

For Off-Label Uses

These are not prescribing guidelines per se. For consumers they are an antidote to the direct-to-consumer marketing phrase “Talk to your doctor about…” regarding the advertised drug. For physicians they are likewise an antidote to drugs being pushed on them by pharm reps.

A synthesis of the literature and consumer experiences can provide good rules of thumb as to when consumers should and should not talk to their doctors, and when doctors should and should not talk to their patients, about particular drugs the first time they discuss treatment options. If at all.

Why/When Abilify (aripiprazole) Should Be Recommended

If you’ve had serious problems with other APs, like:

Why/When Abilify (aripiprazole) Should Not Be Recommended

  • Just thinking about certain foods or certain meds (like Strattera or Depakote) makes you need to take anything in the PeptoBismal to Prilosec spectrum.
  • If you’re already diagnosed with GERD, or something similar, Abilify is in the last resort category.
  • You emptied your bank account at the nearest casino when you took Requip (ropinirole) or Mirapex (pramipexole).


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Dosage, Titration, and Discontinuation

A review of Abilify’s prescribing information, the literature, and consumer experience. We have found that for most consumers in an out-patient situation the titration schedule published in the prescribing information is often too aggressive. Many would often be better served by starting at a dosage lower than recommended by the manufacturer and, instead of a fixed target dosage, the dosage where symptoms are controlled within a given range is the goal. Patients could adjust their dosage as needed without having to schedule an appointment with their prescriber.

Dosage and Doses

As with many APs, BMS recommends you just start at the target dosage. That’s 10–15mg a day for Schizophrenia, 15mg a day for bipolar (as monotherapy), and 10–15mg a day for bipolar (when taken with Depakote or lithium). The maximum dosage is 30mg a day, and you should wait at least two weeks before increasing the dosage.
The only application where you start at a low dosage a move up is when you add it to an AD for depression. That’s when they recommend you start at 2–5mg a day, work up to 5–10mg a day, and the maximum dosage is 15mg a day, and you should wait at least a week before increasing the dosage.

Dosing Schedule

Titration Schedule

One aspect of taking a medication that is frequently missing from patient information, as well as prescribing information, is how to stop taking it. Consumers are left with nothing more than the warning to not stop taking their medication without first talking to their doctor. Circumstances do not always allow for that. Many consumers feel better if they have the knowledge about what they should do.

How to Discontinue

With its long-ass half-lives, a lot easier than most meds.

Discontinuation Symptoms

Notes, Tips, etc. About Discontinuing Abilify



Pros, Cons, and Interesting Information

Even though they want more information than the patient information literature provides, consumers also want a very high-level synopsis. A synthesis of the prescribing information, the literature, and consumer experience provides the pros and cons of using Abilify (aripiprazole) for its approved indications and clinically-significant or otherwise common off-label uses.

Pros

As it sort of acts as a Parkinson’s/RLS med, so you’re somewhat less likely to get a couple of the more annoying AP side effects - most movement disorders and those involving prolactin.
The anticholinergic side effects are also less likely than other APs.
The long half-lives of of Abilify and its active metabolite mean you don’t have to worry about a dosing schedule, and you can even take a tablet every other day.

Cons

Since it kind of acts like a Parkinson’s/RLS med, you can get the oddball side effects of a Parkinson’s/RLS med, like pathological gambling. It also means you can’t take another dopamine agonist to deal with movement disorders and need to take a potent anticholinergic like Cogentin.
Abilify’s long-ass half-lives mean if you two don’t get along you can be stuck with the side effects for at least one, and possibly two weeks after you stop taking it.

When doing their own research about a medication, the educated consumer, and perhaps medical students and healthcare professionals may find interesting pieces of information that are rarely discussed in a prescriber-patient setting. Such information may be rarely discussed because it is trivial, but many people tend to remember interesting, albeit trivial information about something along with other information associated with it. There may be something here to get a patient to remember a more important point about a medication. The other side of that mnemonic coin is what a medication is best known for, something a drug-naïve consumer might not know. While prescribers don’t always assume their patients are aware of a drug’s trait that is “common knowledge,” consumers who do some research don’t want to feel like idiots. They want to know something that isn’t misinformation. Prescribers can always couch questions about well-known traits in forms like “You’re aware that Panacea can cause significant giddiness, right?”

Interesting Things Doctors Rarely Tell Their Patients

Abilify is the first third-generation antipsychotic (TGA) to hit the US market. TGAs are defined as being partial agonists at dopamine D2 receptors, and that’s what makes them act sort of like Parkinson’s/RLS meds. So, unlike Zyprexa, Abilify doesn’t just mask movement disorders by being a potent anticholinergic, it tries to prevent them from happening in the first place.

What Abilify (aripiprazole) is Best Known for

The Abilify Burp.

Noted Traits & Effects



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You don’t have to buy anything. Look around. Share what you like with your Pinterwit friends. Maybe they’ll buy it for you. Probably not.



Adverse Events

A review of prescribing information, the literature, and consumer experiences. One thing this review has found is no matter which neurological/psychiatric drug someone takes, one or more of these adverse events will happen and usually be gone, or at least will diminish to the point where they are barely noticed, within a week or two.

  • Headache
  • Drowsiness/fatigue - even when taking stimulants in some circumstances.
  • Insomnia, instead of or alternating with the drowsiness.
  • Nausea
  • Assorted other minor GI complaints (constipation, diarrhea, etc.)
  • Generally feeling spacey / out of it
    • Which can all add up to the ever-helpful ”flu-like symptoms” listed as an adverse event on the PI sheet of practically every medication on the planet used to treat almost any condition humans and other animals could have.
  • Will affect dreams. There is no way of telling if that will be good or bad, the extent of the change, let alone if this side effect is permanent or temporary.

Potential side effects are often used as a rationalization to not take a medication, and that is a valid reason why prescribers don’t like their patients looking up medications on The Internet. It’s a delicate balancing act between providing too little or too much information about side effects. What may be contrary to popular belief, reports of side effects from consumers on sites run by either medical professionals or consumers themselves are generally not too far outside what is published in the literature after a drug has been on the market.

Common Adverse Events

The usual for antipsychotics (APs), especially:
  • headache
  • agitation
  • akathisia (the inability to sit still)

Unlike almost all other APs, Abilify is more likely to make you hyper instead of turning you into a zombie. So these are far more common with Abilify than other APs:

  • anxiety
  • insomnia
  • non-akathisia restlessness

Additionally there’s:

  • The Abilify Burp - a type of mild-to-moderate gastric reflux. You’ll know it when you taste it.
  • Abilify has so many GI-related side effects that you might as well be taking valproic acid or felbamate.

These side effects are in the “Usually temporary, but they’ll flare up, especially when you change your dosage” category. The only one more likely to stick around than the others is The Burp.

Uncommon Adverse Events

  • blurred vision
  • mania (regardless of your being bipolar or not)
  • teeth grinding & jaw clenching (but rarely progressing to TMJ like Lexapro)
  • muscle aches
  • orthostatic hypotension (getting dizzy, feeling faint and nearly-to-actually passing out when you stand up)
  • While weight gain is less common than most Atypical Antipsychotics (AAPs). Abilify can still hose your blood sugar.

Potentially Dangerous Adverse Events

Neuroleptic Malignant Syndrome (NMS) is rare, but life-threatening (although mainly in people who are over 604) side effect of any AP.

Never underestimate the value of gallows humor when confronted with a condition that comes with the dual stigmata of having a mental illness or other neurological disorder and treating it with a medication that everyone from family members to movie stars and other misinformed celebrities say is worse than the condition itself. It’s not for all consumers, but those who have been using the Internet most of their lives generally appreciate it.

Freaky Rare Side Effects:

Ways to counter / minimize / mitigate / deal with some side effects

Names, Availability, Brand vs. Generic Issues, Forms

Consumers not only travel, they often live in other countries for extended periods. Thus they need to know if the medications they take are available in those countries, what trade names are used, and if the less-expensive generic version is available.

Available as Abilify in these countries

Argentina,Australia,Canada,EU,India,Ireland,Mexico,New Zealand,UK

Other trade name(s) for Abilify used in these countries

エビリファイ: Japan

Generic Name and Availability

US Generic name/INN:aripiprazole
US Generic available?No

aripiprazole is available in these countries5

India

Branded Generic Names6 & Transcribed or Transliterated INN/Generic Name7

  • Arip
  • Aripiprex
  • Asprito
  • aripiprazol


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You don’t have to buy anything. Look around. Tweet what you like with to your Pinbook followers. What else are you doing right now? Working? Yeah, right.



Not all generic medications are created equal. Consumers have noted differences in the quality of medications produced by different manufacturers. See the article on on the differences between brand and generic medications for more information.

Specific generics with complaints, or preferred generics manufacturers

Generics with independently-tested bioequivalence

How Supplied

Available/Supplied As

* Tablets
  • 2 mg green with “A-006” and “2” imprinted
  • 5 mg blue with “A-007” and “5” imprinted
  • 10 mg pink with “A-008” and “10” imprinted
  • 15 mg yellow with “A-009” and “15” imprinted
  • 20 mg white with “A-010” and “20” imprinted
  • 30 mg pink with “A-011” and “30” imprinted
  • Orally Disintegrating Tablets (ODT)
    • 10 mg pink & scattered specks with “A 640” and “10” imprinted
    • 15 mg yellow & scattered specks with “A 641” and “15” imprinted
  • Oral Solution: 1 mg/mL
  • Intramuscular Injection: 9.75 mg/1.3 mL single-dose vial
  • 1% Powder for DIY oral solution (In Japan only, so far as I’ve found.)
Abilify 2 mg tablets
Abilify 2 mg Tablets

Shelf Life

Tablets & ODT - 3 years. Oral solution - 3 years (6 months after opening). IM Injection- 18 months.

Rate this article

If you feel like it, you may rate this article on a scale of 0 (worst) to 5 (best). The more value-judgments the better, even if you can criticize each only once.

Please rate Abilify (aripiprazole): a review of the literature and consumer experience.

4.5 stars Rates 4.5 out of 5 from 6 value judgments.
Vote Distribution: 0 – 0 – 0 – 0 – 3 – 3


Click here for Part 2: Warnings, clinical pharmacology, interactions, additional comments and consumer experiences




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References

  1. Hughes, Shannon, and David Cohen. “Can online consumers contribute to drug knowledge? A mixed-methods comparison of consumer-generated and professionally controlled psychotropic medication information on the internet.” Journal of medical Internet research 13.3 (2011).
  2. Faught, Edward. “Topiramate in the treatment of partial and generalized epilepsy.” Neuropsychiatric disease and treatment 3.6 (2007): 811-821.
  3. Abilify’s Full US Prescribing Information
  4. Mosby’s Drug Consult 2007 (Generic Prescription Physician’s Reference Book Series) © 2007 ISBN:978-0323040587
  5. Article I, Section 8 of the US Constitution
  6. Greenstone Pharmaceuticals’ Product List. Greenstone LLC Last accessed 04 July 2014
  7. History of Pfizer and Warner-Lambert; 2000 to Present. Pfizer.com Last accessed 04 July 2014

{{$$bigbiblio}}


1 Coming from the guy who misses Risperdal because it calms me the hell down when my own Asperger's-inspired irritability gets to be too much. The difference? I'm the one who decided to take Risperdal and deal with TD. How many 6-year-old kids get that option?

2 Before Cymbalta (duloxetine) was approved as an antidepressant in the US it was already approved in the EU, but only for stress urinary incontinence and sold under the trade name Yentreve. Duloxetine is now sold in the EU as an antidepressant under the trade name Cymbalta.
A better known, if slightly different example is bupropion. According to the 2007 edition of Mosby's Drug Consult, and my highly-skilled Google-fu, in the US, Canada and Singapore you can get both Wellbutrin (bupropion) as an antidepressant or as Zyban (bupropion) to stop smoking. In Korea, Thailand and most of South America (but not Brazil) you can get bupropion (under various trade names) only as an antidepressant. In Brazil, the EU & UK, Israel, India, Australia and New Zealand it's only available as Zyban to help you stop smoking.

3 I guess it was sheer luck that not a single person with whom I shared time in the lock ward during my timeout from polite society complained of invisible spiders. So, how many of the people complaining about beg buds in NYC are nutjobs? And how many of the mentally interesting who live on the streets have real lice and other critters living on them?

4 And adolescent males. What do those two groups have in common? They are the two groups of in-patients who are the most likely to be restrained for long periods of time for being "agitated". My guess is many, if not most of the people who died of NMS were restrained and left alone when they presented NMS symptoms such as agitation, "aggressive" breathing, and urinary incontinence. Tied up for peeing? I worked in a nursing home - these days they're called long-term care facilities - in 1980.

5 Generic availability isn't fully harmonized in the EU. Sometimes a drug is available everywhere as a generic, sometimes it's available only in a few member states. We'll provide the best information we have.

6 The term "branded generic" has three meanings:
1) A generic drug produced by a generics manufacturer that is a wholly-owned subsidiary of the company that makes the branded version. E.g. Greenstone Pharmaceuticals makes gabapentin, and they are owned by Pfizer, who also own Parke-Davis, the makers of Neurontin.
2) A branded generic is also a generic drug given a 'brand' name by the manufacturer (e.g. Teva's Budeprion), but otherwise has the same active ingredient as the original branded version (Wellbutrin).
3) A branded generic is also a generic drug given a 'brand' name by the manufacturer (e.g. Sanofi-Aventis' Aplenzin, which is bupropion hydrobromide) and uses a salt of the active ingredient that is different from the original branded version and other generics (Wellbutrin, Budeprion and all the others are bupropion hydrochloride). We aren't sure if that really makes a difference or not. The FDA says they're the same thing. As usual, the data are contradictory, but most evidence indicates that the FDA is right and the differences are negligible.
For our purposes a "branded generic name" refers to the second and third definitions. We'll note if any preferred generics are manufactured by the pioneering company's subsidiary.

7 In some countries the INN / generic name is transcribed into a local phonetic equivalent. In Spanish it's often so close as to be redundant (e.g. topiramato vs. topiramate). In Finnish it's close to being a different drug (e.g. escitalopram vs. essitalopraami). I can understand the need to transliterate the INN / generic name into another alphabet (topiramate becomes топирамат in Russian), but giving a med a different generic name using the Latin alphabet just makes it difficult to find.


If you have any questions not answered here, please see the Crazymeds Abilify discussion board. We welcome criticisms of the articles, notifications of bad links, site problems, consumer experiences with medications, etc. I’m not always able to write back. Hence I never answer questions about meds via e-mail that are answered by this or other articles. Especially if they have been repeatedly asked on the forum. That’s why we write these damn things. Questions about which meds are best for your condition should also be asked on the forum; because this is a free site, so the price of admission is making things easier for somebody else searching for the same answer. We don’t deal with children on the forum or in private because after doing this for ten years I don’t have the emotional stamina to deal with kids who have brain cooties. How to contact Crazymeds. — Jerod Poore, CME, Publisher Crazymeds (crazymeds.net)


Last modified on Monday, 23 September, 2013 at 12:28:23 by JerodPoorePage Author Date created Tuesday, 29 November 2011 at 11:57:45
“Abilify (aripiprazole): a Review for the Educated Consumer.” by Jerod Poore is copyright © 2011 Jerod Poore Published online 2011/11/29
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Plain text:Poore, Jerod. “Abilify (aripiprazole): a Review for the Educated Consumer.” Crazymeds (crazymeds.net). (2011 ).
with Microdata: <span itemprop='citation'>Poore, Jerod. "Abilify (aripiprazole)." <em>Crazymeds (crazymeds.net)</em>.(2011 ).</span>
Linked:<a href="http://scholar.google.com/citations?user=5rkux7sAAAAJ&hl=en&oi=sra">Poore, Jerod</a>. <a href='https://crazymeds.net/pmwiki/pmwiki.php/Meds/AbilifyComprehensiveRundownPart1'>"Abilify (aripiprazole): a Review for the Educated Consumer."</a>. <a href="https://crazymeds.net/pmwiki/pmwiki.php/Main/HomePage"> <em>Crazymeds (crazymeds.net)</em></a>. (2011 ).
with Microdata:<span itemprop='citation'> <a href="http://scholar.google.com/citations?user=5rkux7sAAAAJ&hl=en&oi=sra">Poore, Jerod</a>. <a href='https://crazymeds.net/pmwiki/pmwiki.php/Meds/AbilifyComprehensiveRundownPart1'>"Abilify (aripiprazole): a Review for the Educated Consumer."</a>. <a href="https://crazymeds.net/pmwiki/pmwiki.php/Main/HomePage"> <em>Crazymeds (crazymeds.net)</em></a>. (2011 ).</span>

Abilify, and all other drug names on this page and used throughout the site, are a trademark of someone else. Abilify’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.




Page design and explanatory material by Jerod Poore, copyright © 2003 - 2015. All rights reserved.
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Almost all of the material on this site is by Jerod Poore and is copyright © 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, and 2015 Jerod Poore. Except, of course, the PI sheets - those are the property of the drug companies who developed the drugs the sheets are about - and any documents that are written by other people which may be posted to this site will remain the property of the original authors. You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder. That’s usually me, so just ask first. That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that’s OK to just do. Go for it! Please. As long as you include this copyright notice and something along the lines of following disclaimer, I’m usually cool with it.



All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. If you still have questions about a medication or condition that were not answered on any of the pages you read, please ask them on Crazy Talk: the Crazymeds Forum.
The information on Crazymeds pertains to and is intended for adults. While some information about children and adolescents is occasionally presented (e.g. US FDA approvals), pediatric-specific data such as dosages, side effects, off-label applications, etc. are rarely included in the articles on drugs or discussed on the forum. If you are looking for information regarding meds for children you’ll have to go somewhere else. Plus we are big pottymouths and talk about S-E-X a lot.
Know your sources!
Nobody on this site is a doctor, a therapist, or a pharmacist. We don’t portray them either here or on TV. Only doctors can diagnose and treat an illness. While it’s not as bad as it used to be, some doctors still get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don’t be a cyberchondriac, thinking you have every disease you see a website about, or that you’ll get every side effect from every medication1. Self-prescribing is as dangerous as buying meds from fraudulent online pharmacies that promise you medications without prescriptions.
All information on this site has been obtained from the medications’ product information / summary of product characteristic (PI/SPC) sheets and/or medication guides - which is all you get from sites like WebMD, RxList, NAMBLA NAMI, etc., the sources that are referenced throughout the site, our personal experience and the experiences family, friends, and what people have reported on various reputable sites all over teh intergoogles. As such the information presented here is not intended as a substitute for real medical advice from your real doctor, just a compliment to it. You should never, ever, replace what a real doctor tells you with something from a website on the Internet. The farthest you should ever take it is getting a second opinion from another real doctor. Educate yourself - always read the PI/SPC sheet or medication guide/patient information leaflet (PIL) that comes with your medications and never ever throw them away. OK, you can throw away duplicate copies, but keep at least one, as that’s your proof of purchase of having taken a med in case a doctor doubts your medical history. Plus they take up less space than a bottle, although keeping one inside of a pill bottle is even better.
Crazymeds is not responsible for the content of sites we provide links to. We like them, or they’re paid advertisements, or they’re something else we think you should read to help you make an informed decision about a particular med. Sometimes they’re more than one of those things. But what’s on those sites is their business, not ours.
Very little information about visitors to this site is collected or saved. From time to time I look at search terms used and which pages they bring up in an effort to make the information I present more relevant. And the country of origin, just because I’m geeky like that. That’s about it. Depending on how you feel about Schrodinger, our privacy policy should either assuage or exacerbate your paranoia.
Crazymeds is optimized for ridiculously large screens and browsers that don’t block ads. I use Firefox and Chrome, running under Windows 72. On a computer that sits on top of my desk. With a 23 inch monitor. Hey, at least you can make the text larger or smaller by clicking on the + or - buttons in the upper right hand corner. If you have Java enabled. Like 99% of the websites on the planet, Crazymeds is hosted on domain running an open source operating system with a variety of open source applications, including the software used to display what you’ve been reading. As such Crazymeds is not responsible for whatever weird shit your browser does or does not do when you read this site3.
No neurologists, psychiatrists, therapists or pharmacists were harmed in the production of this website. Use only as directed. Void where prohibited. Contains nuts. Certain restrictions may apply. All data are subject to availability. Not available on all mobile devices, in the 12 Galaxies Guiltied to a Zegnatronic Rocket Society, or in all dimensions of reality. Hail Xenu!

‘Everything is true, nothing is permitted.’ - Jerod Poore


1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.

2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more. With TOS Star Trek movies you don’t want to bother watching the odd-numbered ones. With Microsloth OS you don’t want to buy and install the even-numbered ones. Anyone who remembers ME and Vista knows what I mean.

3 Have I mentioned how open source operating systems for commercial applications is one of the dumbest ideas in the history of dumb ideas?* I don’t even need my big-ass rant any more. Heartbleed has made my case for me. And that’s just the one that got all the media attention. The very nature of an open source operating system makes security as much of an illusion as anonymity on teh Intergoogles. Before you flip out too much: the domain Crazymeds is hosted on uses a version of SSL that is not affected by the Heartbleed bug. That’s one of the many reasons why I pay a lot of money and keep this site on Lunarpages.

* Yes, I know I’m using open source browsers. I also test the site using the now-defunct IE and Safari browsers. Their popularity - and superiority - killed IE and Safari, so that’s why I rely on the open source browsers. It’s like brand vs. generic meds. Sometimes the generic is better than the brand.

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