Medicated For Your Protection
I Forgot Why I Cake Topamax
Table of Contents (hide)
- 1. Discussion Board
- 2. Official US website
- 3. Other official websites
- 4. MultiPageMedicationArticle (longmed) Prescribing Information & Information for Patients
- 5. Other Sites with Consumer/Patient Ratings/Reviews of MultiPageMedicationArticle (longmed)
- 6. Other sites of interest
Crazymeds Manifesto If this were a drug company’s page I’d give you an idea of what is on it.
Most of the time these will be:
- Sites used for different aspects/forms of a drug that have different names
- Like Invega Sustenna’s site.
- Different sites or parts of a site for conditions that aren’t, or are no longer, the primary condition being treated.
- Such as Topamax for epilepsy or practically all second- and third-generation antipsychotics for schizophrenia.
- Official sites for drug in countries other than the US - which are a lot rarer than I thought they would be.
For example, Crazymeds’ Empire of the Shunned:
- The Crazymeds Imperial Corporate Facebook page
- Crazymeds’ Google+ page
- Crazymeds’ Twitter Account
- Crazymeds: The Blog
- Straitjacket T-Shirts
We try to get the most recent prescribing information (PI) sheet available, preferably from the drug company’s web site. If there isn’t one (web site or copy of the PI sheet) the next stop is the FDA. PI sheets are designed for doctors and pharmacists. Information for patients is included with PI sheets that conform to the recently-instituted standards for PI sheets.
These are the additional PI sheets some meds need for other forms, usually because one form will be approved for more, fewer, or completely different conditions than the one ‘regular’ (i.e. more popular) form we use as the basis for these pages.
There will be entries here if a drug has multiple PI sheets for different forms, like the three PI sheets for the three different flavors of Wellbutrin: Immediate Release, Sustained Release (Wellbutrin SR) and eXtended reLease (Wellbutrin XL).
4.3 International Prescribing Information for MultiPageMedicationArticle (longmed): PILs, PMs, SPCs, CMIs, MDSes & EPARs
PI = Prescribing Information PIL = Patient Information Leaflet PM = Product Monograph SPC = Summary of Product Characteristics CMI = Consumer Medicine/Medical Information MDS = Medicine Data Sheet EPAR = European Public Assessment Reports
See the page on how to read our drug guides for detailed translations and explanations of these and other prescribing information-related initialisms & acronyms.
Different countries have different documentation standards and names for the information you’ll find on them. As in the US, some are geared for doctors and pharmacists, while others are for consumers. Some countries even have multiple forms and names. The default terms I use for any
commie metric non-US documents about medication are
- SPC: Summary of Product Characteristics. The equivalent to the US PI and the term used by most other countries. SPCs usually have less information than US PI sheets, but some, especially the British, Irish, and newer EU ones, will have as much, if not more. This page explains a lot of the terms used in English-language SPCs, as well as some used in US PI sheets.
- The initials “SPC” often show up on European SPCs regardless of what the initials are in the document’s language.
- Not in France, of course, where it’s an RCP, or Résumés des Caractéristiques du Produit.
- PIL: Patient/Product Information Leaflet. These are for the consumer/patient. Unlike SPCs, PILs from many other countries often have more information than US PILs/information for patient sheets.
- In most of Europe the full name is usually Package Leaflet: Information for Patients.
- This page explains a lot of the terms used in English-language PILs, including some used in US PILs.
What all the other initials translate to:
- PI: Prescribing Information. What is now the standard name in the US.
- In Australia it’s for Product Information. Here’s a link to an Australian glossary of terms used on most English-language PI/SPC/etc. documents for doctors.
- In South Africa PI means Package Insert. This is the site where the South African PI sheets are hosted.
- PI also means Package Insert Lebanon and Lithuania, but Package Inserts there are consumer-oriented documents.
- In Kazakhstan PI means Prescribing Instructions, and is an SPC.
- MDS: Medicine Data Sheet. A name unique to New Zealand. The format used to be unique as well, now it looks like most other SPCs/PIs.
- Sometimes it’s identical to the Australian PI for a drug.
- Although I’ll come across a med now and then that hasn’t been updated in a long time still in the old MDS format.
- CMI: Consumer Medicine/Medical Information. Australian for “Really comprehensive PIL.”
- The same goes for New Zealand now that they’ve adopted the same term and format.
- EPAR: European Public Assessment Reports. EU1 bureaucratese for an SPC, written in English, with one or more PILs attached to it.
- Multiple PILs are for the different EU languages. Usually there is either one PIL in English or 19, one for each EU language (as of this writing).
- Older EPARs are roughly equivalent to most SPCs, where they have less information than US PI sheets.
- Most SPCs in Europe follow the old EPAR format.
- PM: Health Canada calls their prescribing information Product Monographs.
- Product Monograph the vintage name for PI sheets, and is still used to describe the contents of the PDR.
- Product Monograph (Monografia do Produto) is also used in Brazil, but sometimes it is further refined:
- Informações ao Paciente - Information for Patients - is a PIL
- Informações Técnicas aos Profissionais de Saúde - Technical Information for Healthcare Professionals - is an SPC.
- In the Spanish-speaking countries of Central and South America (i.e. Everywhere except Belize, Brazil, Guiana, Guyana, and Suriname2) I’ve seen two terms used interchangeably for both PILs and SPCs, so you don’t know what the hell you’re getting. More often than not…
- Información Farmacológica is an SPC.
- Prospectus is a PIL.
- Bulgaria calls their PILs Patient Medical Guides.
- Turkey and Russia both use the term Instructions for Use
- In Russia it’s an SPC
- In Turkey it’s a PIL
- Assuming Google translated things correctly, in China and Korea they both use the term Product Manual. As with Russia and Turkey…
- In Korea it’s an SPC
- In China it’s a PIL
- I’ll use the term Drug Information when I find something that looks like a PIL, but isn’t on an official site of any kind and is the only thing I can find that provides any sort of consumer/patient information about a medication in a language or from I country I can’t find. Sometimes these will be from online pharmacies, but you get PILs from pharmacies anyway, right?
- NDA: New Drug Application - the Holy Grail of information about a medication. This is what drug companies have to submit to the FDA to get new drugs approved for use. They include all sorts of stuff, like failed clinical trials. It sometimes takes filing a Freedom of Information Act (FOIA) request and lots of patience to get your hands on one of these.
- RR: Review Report. Japan’s Pharmaceuticals and Medical Devices Agency’s - their version of our FDA - version of an NDA. That is sometimes published online and in English.
- Assessment Report - The EMA’s far more comprehensive version of an NDA. If you ever wanted to know everything that goes into developing a drug this is what you need to read. If you like animals you don’t want to read one, because you may never want to take any medication, including antibiotics and vaccinations, that has been developed since 1930.
Prior to the quasi-standardization we now have in the US the PI in PI sheet stood for3:
- Package Insert - the FDA still uses this term.
- Patient Information - as if most patients could understand more than 10% of what is on a full PI sheet.
- Physician Information
- Prescriber Information - this one was uncommon.
- Prescribing Information - what it now means.
- Product Information
Pile of Pills
Vaccines Cause Immunity
Medicated For Your Protection
I base my odds on how well a drug will work on:
- Clinical trials and other studies published in The Literature.
- Consumer reviews.
- Experiences reported on sites about meds, conditions, or sites that have nothing to do with either, but have a strong demographic overlap4.
- While I write a lot about any personal experience I’ve had with a med, I rarely include that in my calculations on how well a med will work. I know what freaks Mouse and I are.
- So here is where you’ll find the consumer review & rating sites I’ve used or have subsequently found.
- The ones I use most of the time are:
- Ask a patient
- Patients like me
- Psych Central
- I’ll use a couple of reviews of Crazymeds for examples:
- Psych Central’s ratings of Crazymeds - With that many votes you get a fair idea how valuable we are to consumers.
- Viewpoints’ reviews & ratings - about as statistically insignificant as you can get. I would not use this site as a gauge of our worth.
- - Dr. Carlat is an actual, practicing shrink. Consumer reviews are important, but not everything.
Consumer rating & review sites tend to skew negative in a way that isn’t in line with the real world. Or maybe they don’t.5 While more people have negative experiences with meds than big pharma would otherwise have you believe, the drugs are rarely as bad as teh Intergoogles usually make them out to be. While most people get more motivated to do something about an event that pissed them off than an event that made them feel better, and in the Eternal September6 that helps to define the ecology of teh Intertubes, people are more than happy to extrapolate the specific to the general as loudly, passionately, frequently, and often ignorantly as possible, it turns out that consumer review sites are relatively balanced sources of information. At least the ones that don’t specialize in nothing but side effects, and have enough reviews to be statistically significant.7
Most of the time these will be pages with something other than rehashed PI sheets or lots of pharmacology to geek out over:
- DrugsDB - consumer information that isn’t just the regurgitated PI or PIL like everything that shows up in the top ten results of a Google search.
- For the pharmacology geeks
Examples for Crazymeds:
Don’t worry about actually buying one. Windows shop and share the designs you’d like to buy or find worthy of ridicule. What else are you doing now? Working? Sure you are.
||Keep Crazymeds on the air.
Donate some spare electronic currency
you have floating around The Cloud
2 As if I've seen an SPC or PIL from any of those places other than Brazil. The only document I have from the Caribbean is a crappy Celexa SPC from the Dominican Republic.
3 Just in the US. That I've found over the last 12 years. There could be more.
4 Unless you fall into either or both populations you may not have any idea how many women with bipolar 2 are fanatical scrapbookers. There are similar demographic overlaps for other conditions. No, I won't go into them. If Big Pharma isn't going to buy ads on this site they can do their own legwork.
5 See http://www.jmir.org/2011/3/e53/ that uses Crazymeds as a primary source of data. I feel so…Fox News skewered by The Daily Show, as this study uses my own website to contradict what I originally thought to be the case.
6 The September That Never Ended, AKA the Eternal September:
Significance and historical perspective: http://meatballwiki.org/wiki/TheSeptemberThatNeverEnded
First Use: http://groups.google.com/group/alt.folklore.computers/msg/4bd75d223b992e8d
7 Which is why you won't see sites like patientsville.com, rateadrug.com, or rateitall.com. Other sites are included only if there are enough reviews to be statistically significant, which is over 50 in my book. I don't include Consumer Reports' "best buys," because they lump all applications together and add too much weight to cost. Sorry CR, while generic divalproex sodium may be a first-line AED for some forms of bipolar disorder, it isn't for most types of migraines, and it certainly is not a first-line med for fibromyalgia (http://www.consumerreports.org/health/resources/pdf/best-buy-drugs/Anticonvulsants-FINAL.pdf#page=18). But at least you know what the real generic for Depakote is, which is better than 90% of medication-specific sites out there.
If you have any questions not answered here, please see the Crazymeds MultiPageMedicationArticle discussion board. We welcome criticisms of the articles, notifications of bad links, site problems, consumer experiences with medications, etc. I’m not always able to write back. Hence I never answer questions about meds via e-mail that are answered by this or other articles. Especially if they have been repeatedly asked on the forum. That’s why we write these damn things. Questions about which meds are best for your condition should also be asked on the forum; because this is a free site, so the price of admission is making things easier for somebody else searching for the same answer. We don’t deal with children on the forum or in private because after doing this for ten years I don’t have the emotional stamina to deal with kids who have brain cooties. How to contact Crazymeds. — Jerod Poore, CME, Publisher Crazymeds (crazymeds.net)
|Last modified on Saturday, 15 November, 2014 at 14:55:17 by JerodPoore||Page Author Jerod Poore||Date created|
|“MultiPageMedicationArticle (longmed): a Review for the Educated Consumer.” by Jerod Poore is copyright © 2014 Jerod Poore||Published online 1969/12/31|
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|Plain text:||Poore, Jerod. “MultiPageMedicationArticle (longmed): a Review for the Educated Consumer.” Crazymeds (crazymeds.net). (2014 ).|
MultiPageMedicationArticle, and all other drug names on this page and used throughout the site, are a trademark of someone else. MultiPageMedicationArticle’s PI Sheet will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.
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Almost all of the material on this site is by Jerod Poore and is copyright © 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, and 2015 Jerod Poore. Except, of course, the PI sheets - those are the property of the drug companies who developed the drugs the sheets are about - and any documents that are written by other people which may be posted to this site will remain the property of the original authors. You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder. That’s usually me, so just ask first. That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that’s OK to just do. Go for it! Please. As long as you include this copyright notice and something along the lines of following disclaimer, I’m usually cool with it.
All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. If you still have questions about a medication or condition that were not answered on any of the pages you read, please ask them on Crazy Talk: the Crazymeds Forum.
The information on Crazymeds pertains to and is intended for adults. While some information about children and adolescents is occasionally presented (e.g. US FDA approvals), pediatric-specific data such as dosages, side effects, off-label applications, etc. are rarely included in the articles on drugs or discussed on the forum. If you are looking for information regarding meds for children you’ll have to go somewhere else. Plus we are big pottymouths and talk about S-E-X a lot.
Know your sources!
Nobody on this site is a doctor, a therapist, or a pharmacist. We don’t portray them either here or on TV. Only doctors can diagnose and treat an illness. While it’s not as bad as it used to be, some doctors still get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don’t be a cyberchondriac, thinking you have every disease you see a website about, or that you’ll get every side effect from every medication1. Self-prescribing is as dangerous as buying meds from fraudulent online pharmacies that promise you medications without prescriptions.
All information on this site has been obtained from the medications’ product information / summary of product characteristic (PI/SPC) sheets and/or medication guides - which is all you get from sites like WebMD, RxList,
NAMBLA NAMI, etc., the sources that are referenced throughout the site, our personal experience and the experiences family, friends, and what people have reported on various reputable sites all over teh intergoogles. As such the information presented here is not intended as a substitute for real medical advice from your real doctor, just a compliment to it. You should never, ever, replace what a real doctor tells you with something from a website on the Internet. The farthest you should ever take it is getting a second opinion from another real doctor. Educate yourself - always read the PI/SPC sheet or medication guide/patient information leaflet (PIL) that comes with your medications and never ever throw them away. OK, you can throw away duplicate copies, but keep at least one, as that’s your proof of purchase of having taken a med in case a doctor doubts your medical history. Plus they take up less space than a bottle, although keeping one inside of a pill bottle is even better.
Crazymeds is not responsible for the content of sites we provide links to. We like them, or they’re paid advertisements, or they’re something else we think you should read to help you make an informed decision about a particular med. Sometimes they’re more than one of those things. But what’s on those sites is their business, not ours.
Crazymeds is optimized for ridiculously large screens and browsers that don’t block ads. I use Firefox and Chrome, running under Windows 72. On a computer that sits on top of my desk. With a 23 inch monitor. Hey, at least you can make the text larger or smaller by clicking on the + or - buttons in the upper right hand corner. If you have Java enabled. Like 99% of the websites on the planet, Crazymeds is hosted on domain running an open source operating system with a variety of open source applications, including the software used to display what you’ve been reading. As such Crazymeds is not responsible for whatever weird shit your browser does or does not do when you read this site3.
No neurologists, psychiatrists, therapists or pharmacists were harmed in the production of this website. Use only as directed. Void where prohibited. Contains nuts. Certain restrictions may apply. All data are subject to availability. Not available on all mobile devices, in the 12 Galaxies Guiltied to a Zegnatronic Rocket Society, or in all dimensions of reality. Hail Xenu!
‘Everything is true, nothing is permitted.’ - Jerod Poore
1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.
2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more. With TOS Star Trek movies you don’t want to bother watching the odd-numbered ones. With Microsloth OS you don’t want to buy and install the even-numbered ones. Anyone who remembers ME and Vista knows what I mean.
3 Have I mentioned how open source operating systems for commercial applications is one of the dumbest ideas in the history of dumb ideas?* I don’t even need my big-ass rant any more. Heartbleed has made my case for me. And that’s just the one that got all the media attention. The very nature of an open source operating system makes security as much of an illusion as anonymity on teh Intergoogles. Before you flip out too much: the domain Crazymeds is hosted on uses a version of SSL that is not affected by the Heartbleed bug. That’s one of the many reasons why I pay a lot of money and keep this site on Lunarpages.
* Yes, I know I’m using open source browsers. I also test the site using the now-defunct IE and Safari browsers. Their popularity - and superiority - killed IE and Safari, so that’s why I rely on the open source browsers. It’s like brand vs. generic meds. Sometimes the generic is better than the brand.