17 U.S. Code § 107 - Limitations on exclusive rights: Fair use
Notwithstanding the provisions of sections 106 and 106A, the fair use of a copyrighted work, including such use by reproduction in copies or phonorecords or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use the factors to be considered shall include—
(1) the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes [all mirrored content falls under this clause, any ads present are mirrored from the original site, mirrored content earns me no revenue whatsoever];
(2) the nature of the copyrighted work [this is a unique resource for the mentally ill, and preservation of it can be argued to be incredibly important];
(3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and
(4) the effect of the use upon the potential market for or value of the copyrighted work. [absolutely none whatsoever, as the original work no longer exists anywhere else (outside of whatever bits and pieces archive.org managed to capture) - the original site was intermittantly completely unavailable for a extended period of time before its SSL certificate expired (and was never renewed), and eventually the site went offline for good, then finally the DNS records were removed at some point prior to May 2018, so at this point it is well beyond the 'dead and rotting' stage]
The fact that a work is unpublished shall not itself bar a finding of fair use if such finding is made upon consideration of all the above factors.

This domain is not controlled by Jerod Poore, and I will NOT continue redirecting traffic from this domain to crazymeds.us [as I formerly did] while Jerod continues with his immature temper tantrum over adblock or continues to fail to maintain his site, fucking over his entire community and countless visitors in the process. [belated clarification: with specific regards to the adblock drama I was referring to Poore at one point replacing his entire site with a single page complaining about the amount of revenue lost to users with ad blocking active, which is something that I took extreme exception to because this affected ALL visitors to the site regardless of if or if not they were actually using ad blocking]
This mirror is unfortunately incomplete (and very slightly outdated), as /CrazyTalk/ was not included when I scraped the site (it was far too large to scrape given the site's extremely poor performance, my wish to avoid worsening the poor performance further, and other factors). If you're looking for a replacement forum, I suggest visiting https://www.crazyboards.org/forums/. There are issues with many of the mirrored pages, I am working on identifying and fixing them, but I do not have the time to address every single issue at this moment (although by now the majority of these issues have been resolved). Dynamic content is obviously completely broken (this is beyond my control), and the loss of /CrazyTalk/ is quite bad given how much good user-generated info was on there, but you have Jerod to "thank" for that. Maybe I'll bring it back online at some point, but it wouldn't be the same as before. For now, I suggest visiting CrazyBoards instead.
Note (Oct 9 2018): Infrequent additional updates regarding the status of this site will be posted on https://info.crazymeds.net


Highlighting uses, dosage, how to take and discontinue

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Viibryd’s Side Effects, Warnings, etc. >>

Brand & Generic Names; Drug Classes

US brand name: Viibryd
Generic name: vilazodone

Drug Class(es)

Primary drug class: Antidepressants
Additional drug class(es): Miscellaneous Antidepressants, Serotonin-Selective Reuptake Inhibitors. Even though Viibryd is technically not and SSRI, it may as well be considered one.

Approved & Off-Label Uses (Indications)

Viibryd’s US FDA Approved Treatment(s)

Major Depressive Disorder (MDD). Approved 21 January 2011.

Uses Approved Overseas but not in the US

Off-Label Uses of Viibryd

Anxiety



When & If Viibryd Will Work

Viibryd’s Usual Onset of Action (when it starts working)

At least a month, which surprises me. Given how Viibryd works, including how selective and potent it is, I expected more people to respond sooner. Some people respond sooner, of course, but fewer than I originally thought.

Likelihood of Working

So far it looks as if Viibryd is a decent antidepressant. If your doctor thinks that an SSRI is the way to go based on something more than the basic algorithm of “Give them Celexa first” and you have a strong stomach (i.e. don’t have GI problems as soon as you take any medication, crazy or otherwise), then Viibryd is a pretty good med to start with.

My now-retired doctor said he had “surprisingly” good results from Viibryd. I was in pretty bad shape when I saw him, so I may be misremembering the adjective, but he was very happy with Viibryd, and he knows when someone needs serotonin tweaking and when they don’t.

I’ve been reading other reports in the field. People are reasonably happy with Viibryd. So, for now, Viibryd has moved up from “coin toss” to “more likely to work than not.”

Taking and Discontinuing

How to Take Viibryd

Manufacturers’ Recommendations

Forest Pharmaceuticals and Merck recommend:

The recommended dose for VIIBRYD is 40 mg once daily.
VIIBRYD should be titrated, starting with an initial dose of 10 mg once daily for 7 days, followed by 20 mg once daily for an additional 7 days, and then an increase to 40 mg once daily . VIIBRYD should be taken with food.

--the Viibryd PI sheet

Crazymeds’ Suggestions

At this point we don’t have much to suggest, other than taking it with breakfast instead of dinner when you first try it. Based upon Viibryd’s mechanism of action (how Viibryd works), side effects, and consumer experiences, taking Viibryd in the morning seems to work better for more people.

Since Viibryd tends to take a long time to work it’s hard to tell if staying at 20mg (or even 10mg) for longer than a week would be helpful or not. Obviously if it works at 10 or 20mg, then just stay at that dosage. If the side effects become too harsh at 40mg, and you feel like 20mg of Viibryd was starting to do something, then talk to your doctor ASAP about going back down to 20mg and giving it a chance to work at that dosage.

How to Stop Taking Viibryd (discontinuation / withdrawal)

Manufacturers’ Recommendations

Forest, being Forest, are vague and state the obvious. The only thing helpful they offer is a highly detailed description of SSRI-discontinuation syndrome symptoms:

5.6 Discontinuation of Treatment with VIIBRYD
There have been reports of adverse events occurring upon discontinuation of serotonergic antidepressants, particularly when discontinuation is abrupt, including the following:
dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesia, such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, tinnitus, and seizures.
While these events are generally self-limiting, there have been reports of serious discontinuation symptoms. Monitor patients for these symptoms when discontinuing VIIBRYD. Reduce the dose gradually whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, consider resuming the previously prescribed dose. Subsequently, the dose may be decreased, but at a more gradual rate. --the Viibryd PI sheet

Crazymeds’ Suggestions

As with any potent SSRI: very slowly and carefully. Withdrawing Viibryd the same way you titrated (increased the dosage) should work for most people: from 40mg to 20mg for 7 days, then 10mg for 7 days, then you’re done. You might be able to get a starter kit from your doctor. Some people may need to do 40mg to 30mg to 20mg to 10mg.

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Last modified on Thu, 21 May, 2015 at 14:11:09 by JerodPoorePage Author Date created Saturday, 14 July 2012 at 13:07:53
“Viibryd (vilazodone): Uses and Using” by Jerod Poore is copyright © 2012 Jerod Poore Published online 2012/07/14

Viibryd, and all other drug names on this page and used throughout the site, are the trademarks of someone else.

will probably have the name of the manufacturer and trademark owner (they’re not always the same company) at or near the very bottom. Or ask Google who the owner is. The way pharmaceutical companies buy each other and swap products like Monopoly™ real estate, the ownership of the trademark may have changed without my noticing. It may of changed hands by the time you finished reading this article.



Page design and explanatory material by Jerod Poore, copyright © 2003 - 2015. All rights reserved. See the full copyright notice for full copyright details.
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