17 U.S. Code § 107 - Limitations on exclusive rights: Fair use
Notwithstanding the provisions of sections 106 and 106A, the fair use of a copyrighted work, including such use by reproduction in copies or phonorecords or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use the factors to be considered shall include—
(1) the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes [all mirrored content falls under this clause, any ads present are mirrored from the original site, mirrored content earns me no revenue whatsoever];
(2) the nature of the copyrighted work [this is a unique resource for the mentally ill, and preservation of it can be argued to be incredibly important];
(3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and
(4) the effect of the use upon the potential market for or value of the copyrighted work. [absolutely none whatsoever, as the original work no longer exists anywhere else (outside of whatever bits and pieces archive.org managed to capture) - the original site was intermittantly completely unavailable for a extended period of time before its SSL certificate expired (and was never renewed), and eventually the site went offline for good, then finally the DNS records were removed at some point prior to May 2018, so at this point it is well beyond the 'dead and rotting' stage]
The fact that a work is unpublished shall not itself bar a finding of fair use if such finding is made upon consideration of all the above factors.

This domain is not controlled by Jerod Poore, and I will NOT continue redirecting traffic from this domain to crazymeds.us [as I formerly did] while Jerod continues with his immature temper tantrum over adblock or continues to fail to maintain his site, fucking over his entire community and countless visitors in the process. [belated clarification: with specific regards to the adblock drama I was referring to Poore at one point replacing his entire site with a single page complaining about the amount of revenue lost to users with ad blocking active, which is something that I took extreme exception to because this affected ALL visitors to the site regardless of if or if not they were actually using ad blocking]
This mirror is unfortunately incomplete (and very slightly outdated), as /CrazyTalk/ was not included when I scraped the site (it was far too large to scrape given the site's extremely poor performance, my wish to avoid worsening the poor performance further, and other factors). If you're looking for a replacement forum, I suggest visiting https://www.crazyboards.org/forums/. There are issues with many of the mirrored pages, I am working on identifying and fixing them, but I do not have the time to address every single issue at this moment (although by now the majority of these issues have been resolved). Dynamic content is obviously completely broken (this is beyond my control), and the loss of /CrazyTalk/ is quite bad given how much good user-generated info was on there, but you have Jerod to "thank" for that. Maybe I'll bring it back online at some point, but it wouldn't be the same as before. For now, I suggest visiting CrazyBoards instead.
Note (Oct 9 2018): Infrequent additional updates regarding the status of this site will be posted on https://info.crazymeds.net


Follow these links to the previous and next pages.
< Drug Guide Index >
Clicking on a link in the Table of Contents will take you to that section of the drug guide.

US Brand Name: The drug’s brand/trade/proprietary name in the United States

generic name: The drug’s generic/International Nonproprietary Name (INN)

Other Forms: However else it might be available in addition to the default tablet or capsule. E.g. Oral solution, intramuscular injection (IM).

Class: How we categorized the drug. For the most part it’s the same as the rest of pharmaco-medical-industrial complex. Celexa is an antidepressant (AD), Topamax is an antiepileptic drug (AED). Sometimes we go rogue and classify meds based on how they work and chemical structure and not just their approvals. E.g. We call Strattera an AD and will probably reclassify amoxapine as an antipsychotic.

We also have various sub-classes like serotonin-selective reuptake inhibitors (SSRI) and second-generation antipsychotics (SGA).

1.  Other brand names & branded generic names

This is where we list any other names we know of for a drug, either in the US or in other countries. We’ll indicate the countries where a name is used, if we have that information.
Branded generic is a complicated term and is explained as a footnote on all the pages, including this one1.

2.  FDA Approved Uses

This is what a drug has official approval to be prescribed for in the US.

3.  Off-Label Uses

This is what a drug is prescribed for that it doesn’t have approval for in the US. This includes the clinically significant (i.e. it often works, but for a variety of reasons there’s not enough money to be made to justify the costs of getting FDA approval), the interesting, the complete failures, the dangerous, the desperation moves, and the just plain bizarre. Most of the time there will be links to studies, case reports, etc. to give you an idea of how likely an off-label use might work, is worth exploring, that someone actually did that, etc.

4.  Pros and cons

These should be easy enough to figure out. Please don’t base your decision on whether or not to take a med on this section and side effects alone.

5.  Side Effects

These are nowhere near all the potential side effects a med can have. Just a representative sample.

5.1  Typical Side Effects

Practically everyone who takes this drug will get one or more of these.

5.2  Not So Common Side Effects

You may or may not get one or more of these. Don’t be surprised either way.

5.3  Freaky Rare Side Effects

Included for gallows humor. These are real side effects, either from the PI sheet (no link) or case reports (with a link to the case report). “Rare” means fewer than one person in 10,000 gets one of these.
After reading the PI sheets of well over a hundred meds, as well as being somewhat jaded before the crazy took over my life in late 2001, my idea “freaky” might be far different than yours.

6.  Interesting Stuff Your Doctor Probably Won’t Tell You

Sometimes useful, often not. Especially when it’s a bunch of nutjobs who determine what is “interesting.”

Let’s not forget about the ads. Google went through a lot of trouble to have those spy satellites collect information about you so they could precisely determine which ads you’ll be most likely to respond to.



7.  Dosage and How to Take the Drug

For each approved application we’ll give you what the drug company recommends right out of the PI sheet, followed by our suggestion.
The main difference between the two is practically the same, no matter what the med:

  • We often suggest starting at a lower dosage than the drug companies do.
  • We usually suggest increasing your dosage not only at a slower rate, but only if you need to increase it.
  • Most medications have a target dosage, our target dosage is the one where your symptoms stopped.

We may have suggestions for clinically significant off-label uses as well.
All dosage suggestions are for adults, and are just that, suggestions for you to discuss with your doctor as part of your treatment plan.
How to take the drug is along the lines of with or without food, in the morning or at night, once or twice a day, etc. Most of the time it’s exactly the same as you’ll find in the PI sheet.

8.  How Long a Drug Takes to Work

This is our best guess, based on consumer experiences, information from the books & websites in the bibliography, and the PI sheet.

9.  Half-Life & Average Time to Clear Out of Your System

The half-life is usually from the PI sheet. The average time to clear out of your system is approximately the half-life times five. We’ll be explaining this in excruciating detail on a page about pharmacokinetics.

10.  Shelf Life

Most drugs have an expiration date of one year past their prescribed or distributed date. That’s not usually the case. In this age of both patients and EMTs needing to use expired medications, for one reason or another, a more accurate comes in handy. The US doesn’t require a shelf life to be published on the PI sheet, but the UK and New Zealand do, so this information comes from the UK electronic Medicines Compendium or the New Zealand Medicine Data Sheets database. The FDA does require shelf life to be on the new drug application (NDA), but NDAs are difficult to find and are usually heavily redacted (large amounts of text blacked out, or entire pages omitted)), so it’s easier for me to get that information from sources outside of the US. Where the governments apparently care about the health of their citizens more than corporate profits, or something.

11.  How to Stop Taking a Drug

Our suggestion, so you have something to compare with what your doctor recommends. Unless they have a better idea in the PI sheet, which they usually don’t, or the drug has a generally accepted discontinuation plan, we start with this rule of thumb:
Decrease the dosage by the standard titration amount (whatever the PI sheet tells you to increase the dosage by when you start taking it) the average time it takes to clear from your system.
For example: with most SSRIs that works out to reducing your dosage by 10–20mg a day every five to six days.

12.  Days to Reach a Steady State

How long until you reach the point where most of the effects associated with peaks and valleys of having more-than-usual (right after you take it) and less-than-usual (right before your next dose) amounts in your system smooth out.

13.  How a Drug Works

This isn’t on every page. We do our best to explain the experts’ best guesses.

14.  How a Likely a Drug Will Work

This isn’t on every page. We do our best to give you some realistic odds of how well meds work for various conditions, including off-label applications.

15.  How a Drug Compares with Other Meds

This isn’t on every page. These will be links to various studies comparing a drug with other drugs.

16.  Comments

Whatever else there is to write about.



After that it’s comments members of the Crazymeds forum may have on the drug and/or the article, links to the section of the forum about the drug, a link to the US PI sheet and any other PI sheets we can find, a link to a drug-drug interaction checker, and the bibliography.



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< Drug Guide Index >
Follow these links to the previous and next pages.

1 The term "branded generic" has three meanings:
1) A generic drug produced by a generics manufacturer that is a wholly-owned subsidiary of the company that makes the branded version. E.g. Greenstone Pharmaceuticals makes gabapentin, and they are owned by Pfizer, who also own Parke-Davis, the makers of Neurontin.
2) A branded generic is also a generic drug given a 'brand' name by the manufacturer (e.g. Teva's Budeprion), but otherwise has the same active ingredient as the original branded version (Wellbutrin).
3) A branded generic is also a generic drug given a 'brand' name by the manufacturer (e.g. Sanofi-Aventis' Aplenzin, which is bupropion hydrobromide) and uses a salt of the active ingredient that is different from the original branded version and other generics (Wellbutrin, Budeprion and all the others are bupropion hydrochloride). We aren't sure if that really makes a difference or not. The FDA says they're the same thing. As usual, the data are contradictory, but most evidence indicates that the FDA is right and the differences are negligible.
For our purposes a "branded generic name" refers to the second and third definitions.



Page created by: Jerod Poore. Date created: 31 July 2011 Last edited by:





Page design and explanatory material by Jerod Poore, copyright © 2003 - 2015. All rights reserved.
Keep up with Crazymeds and and/or my slow descent into irreparable madness boring life. Pick your preferred social media target(s):

Almost all of the material on this site is by Jerod Poore and is copyright © 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014, and 2015 Jerod Poore. Except, of course, the PI sheets - those are the property of the drug companies who developed the drugs the sheets are about - and any documents that are written by other people which may be posted to this site will remain the property of the original authors. You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder. That’s usually me, so just ask first. That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that’s OK to just do. Go for it! Please. As long as you include this copyright notice and something along the lines of following disclaimer, I’m usually cool with it.



All rights reserved. No warranty is expressed or implied in this information. Consult one or more doctors and/or pharmacists before taking, or changing how you take any neurological and/or psychiatric medication. Your mileage may vary. What happened to us won’t necessarily happen to you. If you still have questions about a medication or condition that were not answered on any of the pages you read, please ask them on Crazy Talk: the Crazymeds Forum.
The information on Crazymeds pertains to and is intended for adults. While some information about children and adolescents is occasionally presented (e.g. US FDA approvals), pediatric-specific data such as dosages, side effects, off-label applications, etc. are rarely included in the articles on drugs or discussed on the forum. If you are looking for information regarding meds for children you’ll have to go somewhere else. Plus we are big pottymouths and talk about S-E-X a lot.
Know your sources!
Nobody on this site is a doctor, a therapist, or a pharmacist. We don’t portray them either here or on TV. Only doctors can diagnose and treat an illness. While it’s not as bad as it used to be, some doctors still get pissed off by patients who know too much about medications, so tread lightly when and where appropriate. Diagnosing yourself from a website is like defending yourself in court, you suddenly have a fool for a doctor. Don’t be a cyberchondriac, thinking you have every disease you see a website about, or that you’ll get every side effect from every medication1. Self-prescribing is as dangerous as buying meds from fraudulent online pharmacies that promise you medications without prescriptions.
All information on this site has been obtained from the medications’ product information / summary of product characteristic (PI/SPC) sheets and/or medication guides - which is all you get from sites like WebMD, RxList, NAMBLA NAMI, etc., the sources that are referenced throughout the site, our personal experience and the experiences family, friends, and what people have reported on various reputable sites all over teh intergoogles. As such the information presented here is not intended as a substitute for real medical advice from your real doctor, just a compliment to it. You should never, ever, replace what a real doctor tells you with something from a website on the Internet. The farthest you should ever take it is getting a second opinion from another real doctor. Educate yourself - always read the PI/SPC sheet or medication guide/patient information leaflet (PIL) that comes with your medications and never ever throw them away. OK, you can throw away duplicate copies, but keep at least one, as that’s your proof of purchase of having taken a med in case a doctor doubts your medical history. Plus they take up less space than a bottle, although keeping one inside of a pill bottle is even better.
Crazymeds is not responsible for the content of sites we provide links to. We like them, or they’re paid advertisements, or they’re something else we think you should read to help you make an informed decision about a particular med. Sometimes they’re more than one of those things. But what’s on those sites is their business, not ours.
Very little information about visitors to this site is collected or saved. From time to time I look at search terms used and which pages they bring up in an effort to make the information I present more relevant. And the country of origin, just because I’m geeky like that. That’s about it. Depending on how you feel about Schrodinger, our privacy policy should either assuage or exacerbate your paranoia.
Crazymeds is optimized for ridiculously large screens and browsers that don’t block ads. I use Firefox and Chrome, running under Windows 72. On a computer that sits on top of my desk. With a 23 inch monitor. Hey, at least you can make the text larger or smaller by clicking on the + or - buttons in the upper right hand corner. If you have Java enabled. Like 99% of the websites on the planet, Crazymeds is hosted on domain running an open source operating system with a variety of open source applications, including the software used to display what you’ve been reading. As such Crazymeds is not responsible for whatever weird shit your browser does or does not do when you read this site3.
No neurologists, psychiatrists, therapists or pharmacists were harmed in the production of this website. Use only as directed. Void where prohibited. Contains nuts. Certain restrictions may apply. All data are subject to availability. Not available on all mobile devices, in the 12 Galaxies Guiltied to a Zegnatronic Rocket Society, or in all dimensions of reality. Hail Xenu!

‘Everything is true, nothing is permitted.’ - Jerod Poore


1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. Then again, staying off of the Internet is a large part of curing/managing the disorder.

2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more. With TOS Star Trek movies you don’t want to bother watching the odd-numbered ones. With Microsloth OS you don’t want to buy and install the even-numbered ones. Anyone who remembers ME and Vista knows what I mean.

3 Have I mentioned how open source operating systems for commercial applications is one of the dumbest ideas in the history of dumb ideas?* I don’t even need my big-ass rant any more. Heartbleed has made my case for me. And that’s just the one that got all the media attention. The very nature of an open source operating system makes security as much of an illusion as anonymity on teh Intergoogles. Before you flip out too much: the domain Crazymeds is hosted on uses a version of SSL that is not affected by the Heartbleed bug. That’s one of the many reasons why I pay a lot of money and keep this site on Lunarpages.

* Yes, I know I’m using open source browsers. I also test the site using the now-defunct IE and Safari browsers. Their popularity - and superiority - killed IE and Safari, so that’s why I rely on the open source browsers. It’s like brand vs. generic meds. Sometimes the generic is better than the brand.


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